LSU won the toss and deferred to the second half. Auburn chose to receive and LSU defended the south end zone.
Kickoff was at 2:40 p.m. CT.
Game attendance was announced as a sellout of 87,451.
LSU now leads the all-time series 23-20-1, but Auburn now has a 10-6 edge in games played in Auburn.
Auburn's win over No. 6 LSU marked the highest-ranked team that the Tigers have beaten since a victory at No. 4 Florida on Sept. 29, 2007.
Auburn has now won 10 of its last 17 games against teams ranked in the top 10 of the Associated Press poll, and has 16 wins over top-10 teams since 2001.
Auburn improved to 8-0 for the first time since 2004 and the eighth time in school history.
Auburn finished with 526 yards rushing, and had 145 at the half. LSU entered the contest allowing just 83.6 yards rushing per game.
Auburn rushed for more than 300 yards for the fourth straight SEC game. Since records are available beginning in 1967, Auburn had never had as many as three straight 300-yard rushing games against SEC teams.
Auburn's 526 yards is the most allowed by LSU's defense this season and no SEC opponent had more than 268 yards of total offense against LSU this season.
Auburn's 440 yards rushing is the fifth-most in Auburn history and the most ever against a SEC opponent.
Auburn's 86 yards passing is the fewest yards passing in a SEC victory since beating Mississippi State, 16-14, in 2001.
The score was tied at halftime, 10-10, marking the first Auburn game this season to be tied at halftime. Auburn trailed at the half against Clemson and South Carolina.
Auburn led 17-10 after three quarters. The Tigers have led after the third period in every game but South Carolina (trailed) and Kentucky (tied).
Auburn had its second scoring drive of more than 90 yards this season with a 3-play, 91-yard drive in the third quarter.
OT Lee Ziemba extended his consecutive starts streak to 46 games, which is three shy of the school record held by Will Herring.
Wes Byrum became Auburn's all-time leading scorer with a 42-yard field goal in the second quarter. Byrum finished the game scoring six points to move past John Vauhgn (2003-06) for the school lead with 315 career points.
Cam Newton finished with 217 yards rushing on 28 carries, pushing his season total to 1,077 yards and breaking the SEC single-season rushing record for a quarterback. Auburn's Jimmy Sidle held the record of 1,006 yards in 1963.
Newton's 217 rushing yards is the most of his career and ranks 15th Auburn history for rushing in a game.
Newton now owns five of the top 50 rushing performances in Auburn history despite having played just eight games for the Tigers.
Newton posted the 19th 1,000-yard rushing season in Auburn history and the second in as many seasons.
Newton had a 1-yard TD rush in the first quarter and a 49-yarder in the third quarter. His second TD run broke the Auburn single-season record for TDs responsible for in a season, pushing him one ahead of Pat Sullivan's record of 26 set in 1970.
Newton now has 14 rushing touchdowns, which ties for the fourth most in a single season in Auburn history and is just three shy of the school record.
Michael Dyer rushed for 100 yards, marking his second 100-yard rushing game (South Carolina). It also marked the second time this season that Auburn had two players go over 100 yards rushing in the same game, as Newton and Dyer accomplished the feat against the Gamecocks.
Mario Fannin had 34 all-purpose yards, moving past James Joseph (1987-90) into 10th in Auburn history for career all-purpose yards with 3,117. He had 29 rushing yards, passing Fred Beasley (1994-97) for 29th in Auburn history in rushing with 1,224 yards.
Darvin Adams caught three passes for 33 yards, moving into 10th place in Auburn history for career receiving yards with 1,467 and into 14th place in AU history for career receptions with 89.
Zac Etheridge ended LSU's opening drive with his second interception of the season and the third of his career. His 33-yard return was a career long and tied for the longest of the year by an Auburn player (Josh Bynes vs. Arkansas).
Nick Fairley had 2.5 sacks and 3.5 tackles for loss, continuing his streak of having at least one tackle for loss in every game this season.
Josh Bynes led the defense with 11 tackles. It was the sixth game in his career with double-digit tackles.
Ontario McCalebb's 70-yard touchdown run at 5:05 in the fourth quarter was his fourth of the season and the eighth of his career. It was the longest touchdown run of his career.